AS part of a major drug operation, Mildura police have charged 12 members of a drug syndicate, and will allege they trafficked $150,000 of ice through Mildura, Swan Hill and Kerang each week.

Mildura superintendent John O'Connor said across the past five months the Mildura Divisional Response Unit have been heading Operation Zena, which targeted drug trafficking in the three Victorian towns.

"I'...